diff --git a/content/post/biological-sex.md b/content/post/biological-sex.md new file mode 100644 index 0000000..ecac589 --- /dev/null +++ b/content/post/biological-sex.md @@ -0,0 +1,236 @@ ++++ +title = "Biological sex" +date = "2019-12-23" +tags = ["biology"] ++++ + +# DRAFT + +### "Biological Sex" + +This is a term I've been bumping up against on various online communities +recently - usually in discussions about (or, more accurately, against) trans +people, but it shows up in other contexts too. + +Being a (lapsed) biologist, I have Opinions about this term. Rather than repeat +the same case over and over again in these discussions, I'm laying it out here +for easy linking, and to act as a sort of persistent memory of my conversations +on this topic. If I've linked you to this page, you've probably used the term +where I could hear you, and I am now grumpy at you. This is easily resolved - +read the page, think carefully about its implications for what you are saying, +and act or respond accordingly. If you think the positions or ideas on this page - +either my own, or those I'm representing on behalf of others - need changes, +let me know. We can talk about it. + +Anyway, what is "biological sex"? + +The people using it seem to want a static label for people - "male" or "female" +(sometimes "hermaphrodite" is recognised, sometimes not). The categories and +their immutability are asserted because "sex is biological". As a (very sad, +purely coincidental, honest guv) consequence, trans men aren't, and neither are +trans women. Gender theory is entirely bypassed - you are your biological sex +(curiously, this is usually identical to the gender you were assigned at birth), +and you will be that forever. There is no point to reassignment surgery, and +your pronouns absolutely must be determined from this datum, as must the +bathroom you use, the sports competitions you take part in, and the systemic +biases or privileges you suffer or benefit from. + +This position is upsetting to various people, and I don't like it myself, but as +a biologist, I have a very specific question - **which** definition of +"biological sex" are we using here? + +That animals (and, by extension, humans) have multiple sexes is definitely not +in doubt, but for biologists, the term means different things in different +contexts . Even when restricting the discussion to just humans, we can talk +about sex as a genotypical, phenotypical, or even neurotypical attribute. +Biologists may assign one person to different categories for each definition, +depending on circumstances. + +Which definition were you thinking of when you said "biological sex" to me? +Maybe jump straight to that section. If you weren't thinking of one at all, +maybe you've got a problem - start at the top. If you were thinking of one that +I've not listed, maybe I've got a problem - tell me about it. + +#### Genotype + +In this model of biological sex, men are `XY`, women are `XX`, and you can work +out which sex you are by karyotyping. Anyone can do it - all you need is a swab, +a light microscope, and a bit of stain. It's irrefutable. Sorry, trans people - +if your karyotype disagrees with your feelings, that's just reality come to +call. This is probably what most people implicitly think of when talking about +biological sex. + +The biggest question I have about this model is why we would use it in the first +place. Fundamentally - why does it matter what karyotype people are? How does +this characteristic feed into decisions people make about other people when, +even though it's so easy and simple to do, karyotyping is almost never done, and +plays almost no role in human social interaction? Why do we pick this attribute? +To me, it looks like it's just a fairly good **proxy** for things that people +care about, rather than being the cared-about thing itself. + +Note that there are *other* possible sets of sex chromosomes in humans. There +are, in fact, six reasonably-common permutations: + +* `XX` - Female +* `XY` - Male +* `X` - Turner's syndrome +* `XXY` - Klinefelter's syndrome +* `XYY` - XYY syndrome +* `XXYY` - XXYY syndrome + +Approaches to managing this extra complexity vary - you could declare there are +more than two biological sexes, for instance, or that being biologically male is +all about having at-least-one Y chromosome. The former is very uncommon, but if +karyotype itself matters, rather than being a proxy for something, I'd expect +people to take it. + +Some examples of outliers may be instructive here. Yes, outliers. Theories are +tested against anomalous data - Einstein's model of gravity works where Newton's +doesn't, and we'll all be much happier when we find something that works where +both fail. If biological sex is a biological concept, it needs to run the same +gauntlet. + +To pick on sports performance for a moment - we don't actually know which +karyotypes [Caster Semenya](https://en.wikipedia.org/wiki/Caster_Semenya) or +[Dutee Chand](https://en.wikipedia.org/wiki/Dutee_Chand) have, but measures +against them have focused on other attributes, like testosterone levels. Being +uncharitable to the IAAF, this suggests to me that they have an `XX` karyotype, +but the governing body still isn't happy with them competing. In any case, we +can certainly imagine athletes like them existing with an `XX` karyotype. + +Why don't we karyotype all athletes and use that as the sole basis of sex here? +Would that solve all these issues, in your view? + +Another example: if a +person who is a [mosaic of `X` and `XY` cells](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190741/) +has given birth to a child, what is the biological sex of the parent, and are +they a mother, or a father? + +Yup, people can be several different karyotypes **at the same time**. Does this +mean that they're multiple sexes at the same time? Do we take the most prevalent +karyotype? Are different parts of them different sexes? How does this feed into +policy? + +This person is almost entirely `XY`-karyotype. Does this mean they're male, and +should be treated as such? If not, why not? + +For some reason, despite the fact that a simple karyotype would have returned +`XY`, this person was assigned female at birth. They grew up as a woman, and had +a baby in due course via the usual mechanisms. I don't know if they were into +sport or not, though. + +Are they, then, a woman? If not, why not? + +If you're thinking something along the lines of "congratulations, he's a new +father, but I really think he should stop entering women's bathrooms and sports +competitions" - well, you're consistent, at least, but please do tell me **why** +you think karyotype should determine this, because I can't think of a good +reason for it. + +Most people either already knew, or are perhaps now in the process of realising, +that this version of biological sex doesn't encapsulate their beliefs at all. +Which leads us on to... + +#### Phenotype + +Genotype plus interaction with environment equals phenotype. This is a very +broad statement, but out of it falls all of developmental biology, morphology, +etc. Typically, but not always, `XX` people will have no penis, but breasts, +vagina and womb; cyclical oestrogen; and low testosterone. `XY` people will +typically have a penis but no breasts, vagina, or womb; fairly stable oestrogen; +and higher levels of testosterone. I submit that this is the kind of thing +people generally *mean* when they talk about biological sex, even though they're +*thinking* about genotype. + +In support of this submission, note that this tidies up the outlier we found +earlier - now an `XY` person who is "phenotypically female" can give birth and +enter women's bathrooms without contradiction - and this is what people +**actually** use, instead of karyotyping, to assign gender most of the time. + +However, we need to let go of something very important here. Unlike genotype, +phenotype can - and invariably does - change over time. By moving away from +"genotype", we have lost the part of "biological sex" that was initially most +attractive about it in the context of this discussion - immutability. Suddenly, +one's "biological sex" is mutable, and it can change - or be changed - over +time. + +Hopefully the implications of that are clear, but there are a few angles that +should be specifically addressed. + +##### "Only your phenotype at birth matters" + +Why? I was born with two legs, but if one comes off somehow, my phenotype is now +"one-legged". This is not negotiable. Treating me as if I have two legs, just +because I was born with two, is not going to be good for me, and you're going to +look like a right prick at airport security when you take my crutch away. + +##### "Reproduction is the key part of the phenotype" + +Is it? Is it really? How do we account for people who are capable of +reproducing, but choose not to? Or infertile people? Do women stop being women +at menopause? Do men stop being men post-vasectomy? What do they become, if so? + +What elevates this one aspect of human experience into the determinative one, +anyway? On whose authority? Note that evolutionary teleology is not an answer. + +##### "Trans women phenotypes are not identical to cis women phenotypes" + +Certainly true. In other, entirely unrelated news, rich women phenotypes are not +identical to poor women phenotypes. + +This objection is often a repetition of "Reproduction is the key part of the +phenotype", so you might want to read that as well. + +##### "You're making it far too complicated, biological sex is just common sense" + +Appeals to common sense are a particularly pernicious form of conservatism that +I have no truck with. There is truthiness to the term "biological sex", but it +falls apart upon careful examination. So kindly stop using it. + +If you must persist with the general idea, consider using the term "genotypical +sex", "phenotypical sex", or some other, more accurate, qualifier, so we can at +least start this conversation from a different point in the future. + +##### What attributes determine phenotypical sex anyway? + +It's easy to put most people into one sex category or another, phenotypically - +as I noted above, penises and vaginas are how assignments are usually made at +birth. However, as with genotype, there are instructive outliers here. How do +we decide when it's not obvious at first glance, and what does this tell us +about "phenotypical sex"? + +The obvious first bite is hermaphrodism, or people who have some form of sexual +indeterminacy at birth. What we do here is variable - but sometimes includes +surgical intervention to make one's phenotype "unambiguous". Often this is a +matter of judgement by the surgeon. What happens if they get it wrong? What does +it *mean* to get it wrong? + +With adults, the phenotypical cues we use in the street to determine which +category we put people into vary - and we quite often get it wrong. For many +years, I had long hair. This often caused people to identify me as a woman, +leading to embarrassment, confusion, and not a few cases of violence, when they +realised their mistake. + +Is long hair a biological trait of women, or does culture determine whether long +hair connotates one sex or another? I think you know the answer. + +Do you now agree that cultural has at least some part in determining what it +means to be phenotypically male, or female? If not, why not? + +#### Neurotype + +Just as a brief coda - biologists have other definitions of sex, too. One of +those is neurotype - the idea that a person's brain may be morphologically male +or female (with the same caveats as above). This is mostly a specialism of +phenotype, and nobody's resorted to it yet. Maybe I'll get to fill it out in the +future. + +#### tl;dr + +* Biologists do not have a single concept of sex +* The term "biological sex" elides attributes of genotype and phenotype +* Genotypical sex is only a proxy for phenotypical sex +* The categories of sex found in phenotype are **at least partly** socially determined +* Although genotypes are fairly immutable, phenotypes are very mutable +* Some people changing their phenotype are trans people +* You cannot short-circuit gender theory by appeal to "biological sex"